miR-497 suppresses cycle progression through an axis involving CDK6 in ALK-positive cells

Anaplastic large-cell lymphoma, a T-cell neoplasm, is primarily a pediatric disease. Seventy-five percent of pediatric anaplastic large-cell lymphoma cases harbor the chromosomal translocation t(2;5)(p23;q35) leading to the ectopic expression of NPM-ALK, a chimeric tyrosine kinase. NPM-ALK consists...

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Publicado en:Haematologica
Autores principales: Hoareau-Aveilla, Coralie, Quelen, Cathy, Congras, Annabelle, Caillet, Nina, Labourdette, Delphine, Dozier, Christine, Brousset, Pierre, Lamant, Laurence, Meggetto, Fabienne
Formato: Artigo
Lenguaje:Inglês
Publicado: Ferrata Storti Foundation 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355472/
https://ncbi.nlm.nih.gov/pubmed/30262555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.195131
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