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Preferential Gq signaling in diabetes: an electrical switch in incretin action and in diabetes progression?
Patients with type 2 diabetes (T2D) fail to secrete insulin in response to increased glucose levels that occur with eating. Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are two incretins secreted from gastrointestinal cells that amplify insulin secretion whe...
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| Publicado en: | J Clin Invest |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7685717/ https://ncbi.nlm.nih.gov/pubmed/33196460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI143199 |
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