Galangin Inhibits LPS-Induced MMP-9 Expression via Suppressing Protein Kinase-Dependent AP-1 and FoxO1 Activation in Rat Brain Astrocytes

PURPOSE: Neuroinflammation, characterized by the increased expression of inflammatory proteins such as matrix metalloproteinases (MMPs), plays a critical role in neurodegenerative disorders. Lipopolysaccharide (LPS) has been shown to upregulate MMP-9 expression through the activation of various tran...

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Detalhes bibliográficos
Publicado no:J Inflamm Res
Main Authors: Yang, Chien-Chung, Hsiao, Li-Der, Yang, Chuen-Mao
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685391/
https://ncbi.nlm.nih.gov/pubmed/33244253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S276925
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