Pristimerin Inhibits MMP-9 Expression and Cell Migration Through Attenuating NOX/ROS-Dependent NF-κB Activation in Rat Brain Astrocytes Challenged with LPS

PURPOSE: Neuroinflammation plays a crucial role in neurodegenerative diseases. Matrix metalloproteinases (MMPs) are a landmark of neuroinflammation. Lipopolysaccharide (LPS) has been demonstrated to induce MMP-9 expression. The mechanisms underlying LPS-induced MMP-9 expression have not been complet...

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Vydáno v:J Inflamm Res
Hlavní autoři: Yang, Chien-Chung, Hsiao, Li-Der, Tseng, Hui-Ching, Kuo, Ching-Ming, Yang, Chuen-Mao
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2020
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381777/
https://ncbi.nlm.nih.gov/pubmed/32765041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S252659
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