Carbon Monoxide Releasing Molecule-3 Enhances Heme Oxygenase-1 Induction via ROS-Dependent FoxO1 and Nrf2 in Brain Astrocytes

Carbon monoxide releasing molecule-3 (CORM-3) has been shown to protect inflammatory diseases via the upregulation of heme oxygenases-1 (HO-1). However, in rat brain astrocytes (RBA-1), the mechanisms underlying CORM-3-induced HO-1 remain poorly defined. This study used western blot, real-time PCR,...

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Detalles Bibliográficos
Publicado en:Oxid Med Cell Longev
Main Authors: Lin, Chih-Chung, Yang, Chien-Chung, Hsiao, Li-Der, Yang, Chuen-Mao
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi 2021
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8214505/
https://ncbi.nlm.nih.gov/pubmed/34194603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5521196
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