Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR

Rising numbers of cases of multidrug- and extensively drug-resistant Pseudomonas aeruginosa over recent years have created an urgent need for novel therapeutic approaches to cure potentially fatal infections. One such approach is virulence attenuation where anti-virulence compounds, designed to redu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Eur J Med Chem
Prif Awduron: Grossman, Scott, Soukarieh, Fadi, Richardson, William, Liu, Ruiling, Mashabi, Alaa, Emsley, Jonas, Williams, Paul, Cámara, Miguel, Stocks, Michael J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Editions Scientifiques Elsevier 2020
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7684530/
https://ncbi.nlm.nih.gov/pubmed/32927392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.112778
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