Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR

Rising numbers of cases of multidrug- and extensively drug-resistant Pseudomonas aeruginosa over recent years have created an urgent need for novel therapeutic approaches to cure potentially fatal infections. One such approach is virulence attenuation where anti-virulence compounds, designed to redu...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Grossman, Scott, Soukarieh, Fadi, Richardson, William, Liu, Ruiling, Mashabi, Alaa, Emsley, Jonas, Williams, Paul, Cámara, Miguel, Stocks, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Editions Scientifiques Elsevier 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7684530/
https://ncbi.nlm.nih.gov/pubmed/32927392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.112778
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