Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa

Current treatments for Pseudomonas aeruginosa infections are becoming less effective because of the increasing rates of multi-antibiotic resistance. Pharmacological targeting of virulence through inhibition of quorum sensing (QS) dependent virulence gene regulation has considerable therapeutic poten...

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Bibliografski detalji
Izdano u:Front Chem
Glavni autori: Soukarieh, Fadi, Liu, Ruiling, Romero, Manuel, Roberston, Shaun N., Richardson, William, Lucanto, Simone, Oton, Eduard Vico, Qudus, Naim Ruhul, Mashabi, Alaa, Grossman, Scott, Ali, Sadiqur, Sou, Tomás, Kukavica-Ibrulj, Irena, Levesque, Roger C., Bergström, Christel A. S., Halliday, Nigel, Mistry, Shailesh N., Emsley, Jonas, Heeb, Stephan, Williams, Paul, Cámara, Miguel, Stocks, Michael J.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Chemistry
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213079/
https://ncbi.nlm.nih.gov/pubmed/32432073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.00204
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