Inhibition of Y1 Receptor Promotes Osteogenesis in Bone Marrow Stromal Cells via cAMP/PKA/CREB Pathway

Inhibition of neuropeptide Y1 receptor stimulates osteogenesis in vitro and in vivo. However, the underlying mechanisms involved in these effects remain poorly understood. Here we identify the effects of Y1 receptor deficiency on osteogenic differentiation in human bone marrow stromal cells (BMSCs)...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Yu, Wei, Chen, Fan-Cheng, Xu, Wen-Ning, Ding, Sheng-Long, Chen, Peng-Bo, Yang, Lei, Jiang, Sheng-Dan, Pan, Xiao-Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683715/
https://ncbi.nlm.nih.gov/pubmed/33240219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.583105
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