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Gap Junction-Mediated Intercellular Communication of cAMP Prevents CDDP-Induced Ototoxicity via cAMP/PKA/CREB Pathway

In the cochlea, non-sensory supporting cells are directly connected to adjacent supporting cells via gap junctions that allow the exchange of small molecules. We have previously shown that the pharmacological regulation of gap junctions alleviates cisplatin (CDDP)-induced ototoxicity in animal model...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Kim, Yeon Ju, Lee, Jin-Sol, Kim, Hantai, Jang, Jeong Hun, Choung, Yun-Hoon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231879/
https://ncbi.nlm.nih.gov/pubmed/34199197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126327
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