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Gap Junction-Mediated Intercellular Communication of cAMP Prevents CDDP-Induced Ototoxicity via cAMP/PKA/CREB Pathway

In the cochlea, non-sensory supporting cells are directly connected to adjacent supporting cells via gap junctions that allow the exchange of small molecules. We have previously shown that the pharmacological regulation of gap junctions alleviates cisplatin (CDDP)-induced ototoxicity in animal model...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Kim, Yeon Ju, Lee, Jin-Sol, Kim, Hantai, Jang, Jeong Hun, Choung, Yun-Hoon
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231879/
https://ncbi.nlm.nih.gov/pubmed/34199197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126327
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