Inhibition of Y1 Receptor Promotes Osteogenesis in Bone Marrow Stromal Cells via cAMP/PKA/CREB Pathway

Inhibition of neuropeptide Y1 receptor stimulates osteogenesis in vitro and in vivo. However, the underlying mechanisms involved in these effects remain poorly understood. Here we identify the effects of Y1 receptor deficiency on osteogenic differentiation in human bone marrow stromal cells (BMSCs)...

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Bibliografiske detaljer
Udgivet i:Front Endocrinol (Lausanne)
Main Authors: Yu, Wei, Chen, Fan-Cheng, Xu, Wen-Ning, Ding, Sheng-Long, Chen, Peng-Bo, Yang, Lei, Jiang, Sheng-Dan, Pan, Xiao-Yun
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Endocrinology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683715/
https://ncbi.nlm.nih.gov/pubmed/33240219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.583105
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