Hypoxic Tumor-Derived Exosomal Circ0048117 Facilitates M2 Macrophage Polarization Acting as miR-140 Sponge in Esophageal Squamous Cell Carcinoma

INTRODUCTION: Hypoxia and tumor-associated macrophage (TAM) are key regulators in remodeling the microenvironment of esophageal squamous cell carcinoma (ESCC). Hypoxia could stimulate tumor cells to secrete more exosomes and activate TAMs to M2 type. Here, we investigated the function and the underl...

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Detalles Bibliográficos
Publicado en:Onco Targets Ther
Main Authors: Lu, Qijue, Wang, Xinyu, Zhu, Ji, Fei, Xiang, Chen, Hezhong, Li, Chunguang
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2020
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682796/
https://ncbi.nlm.nih.gov/pubmed/33239890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S284192
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