Hypoxic Tumor-Derived Exosomal Circ0048117 Facilitates M2 Macrophage Polarization Acting as miR-140 Sponge in Esophageal Squamous Cell Carcinoma

INTRODUCTION: Hypoxia and tumor-associated macrophage (TAM) are key regulators in remodeling the microenvironment of esophageal squamous cell carcinoma (ESCC). Hypoxia could stimulate tumor cells to secrete more exosomes and activate TAMs to M2 type. Here, we investigated the function and the underl...

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Bibliografske podrobnosti
izdano v:Onco Targets Ther
Main Authors: Lu, Qijue, Wang, Xinyu, Zhu, Ji, Fei, Xiang, Chen, Hezhong, Li, Chunguang
Format: Artigo
Jezik:Inglês
Izdano: Dove 2020
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682796/
https://ncbi.nlm.nih.gov/pubmed/33239890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S284192
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