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A global analysis of low-complexity regions in the Trypanosoma brucei proteome reveals enrichment in the C-terminus of nucleic acid binding proteins providing potential targets of phosphorylation

Background: Low-complexity regions (LCRs) on proteins have attracted increasing attention recently due to their role in the assembly of membraneless organelles or granules by liquid-liquid phase separation. Several examples of such granules have been shown to sequester RNA and proteins in an inactiv...

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Détails bibliographiques
Publié dans:Wellcome Open Res
Auteurs principaux: Cayla, Mathieu, Matthews, Keith R., Ivens, Alasdair C.
Format: Artigo
Langue:Inglês
Publié: F1000 Research Limited 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682498/
https://ncbi.nlm.nih.gov/pubmed/33274300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.16286.2
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