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Developmental competence and antigen switch frequency can be uncoupled in Trypanosoma brucei

African trypanosomes use an extreme form of antigenic variation to evade host immunity, involving the switching of expressed variant surface glycoproteins by a stochastic and parasite-intrinsic process. Parasite development in the mammalian host is another feature of the infection dynamic, with tryp...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: McWilliam, Kirsty R., Ivens, Alasdair, Morrison, Liam J., Mugnier, Monica R., Matthews, Keith R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842576/
https://ncbi.nlm.nih.gov/pubmed/31636179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912711116
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