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Developmental competence and antigen switch frequency can be uncoupled in Trypanosoma brucei

African trypanosomes use an extreme form of antigenic variation to evade host immunity, involving the switching of expressed variant surface glycoproteins by a stochastic and parasite-intrinsic process. Parasite development in the mammalian host is another feature of the infection dynamic, with tryp...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: McWilliam, Kirsty R., Ivens, Alasdair, Morrison, Liam J., Mugnier, Monica R., Matthews, Keith R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842576/
https://ncbi.nlm.nih.gov/pubmed/31636179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912711116
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