Curtailing FGF19’s mitogenicity by suppressing its receptor dimerization ability

As a physiological regulator of bile acid homeostasis, FGF19 is also a potent insulin sensitizer capable of normalizing plasma glucose concentration, improving lipid profile, ameliorating fatty liver disease, and causing weight loss in both diabetic and diet-induced obesity mice. There is therefore...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Niu, Jianlou, Zhao, Jing, Wu, Jiamin, Qiao, Guanting, Gu, Junlian, Zhou, Chuanren, Li, Qi, Ying, Lei, Wang, Dezhong, Lin, Huan, Li, Xiaokun, Mohammadi, Moosa, Huang, Zhifeng
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682408/
https://ncbi.nlm.nih.gov/pubmed/33144503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2010984117
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