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Paracrine Fibroblast Growth Factor 1 Functions as Potent Therapeutic Agent for Intrahepatic Cholestasis by Downregulating Synthesis of Bile Acid

Endocrine fibroblast growth factor (FGF) 19 has been shown to be capable of maintaining bile acid (BA) homeostasis and thus hold promise to be a potential therapeutic agent for cholestasis liver disease. However, whether paracrine FGFs possess this BA regulatory activity remains to be determined. In...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Lin, Huan, Zhou, Chuanren, Hou, Yushu, Li, Qi, Qiao, Guanting, Wang, Yang, Huang, Zhifeng, Niu, Jianlou
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933012/
https://ncbi.nlm.nih.gov/pubmed/31920680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01515
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