Á lódáil...

Structural Mimicry of A-Loop Tyrosine Phosphorylation by a Pathogenic FGF Receptor 3 Mutation

The K650E gain-of-function mutation in the tyrosine kinase domain of FGF receptor 3 (FGFR3) causes Thanatophoric Dysplasia type II, a neonatal lethal congenital dwarfism syndrome, and when acquired somatically, it contributes to carcinogenesis. In this report, we determine the crystal structure of t...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Huang, Zhifeng, Chen, Huaibin, Blais, Steven, Neubert, Thomas A., Li, Xiaokun, Mohammadi, Moosa
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839590/
https://ncbi.nlm.nih.gov/pubmed/23972473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.07.017
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!