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Hypersensitivity of Vps33B mutant flies to non-pathogenic infections is dictated by aberrant activation of p38b MAP Kinase

Loss of the Arthrogryposis-Renal dysfunction-Cholestasis (ARC) syndrome-linked Vps33B protein results in exaggerated inflammatory responses upon activation of receptors of the innate immune system in both vertebrates and flies. However, little is known about the signaling elements downstream of thes...

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Detalhes bibliográficos
Publicado no:Traffic
Main Authors: Zhang, Jian, Tracy, Charles, Pasare, Chandrashekhar, Zeng, Jinsheng, Krämer, Helmut
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682251/
https://ncbi.nlm.nih.gov/pubmed/32677257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12756
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