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ARC Syndrome-linked Vps33B protein is required for inflammatory endosomal maturation and signal termination

Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs) sense microbial ligands and initiate signaling to induce inflammatory responses. Although the quality of inflammatory responses is influenced by internalization of TLRs, the role of endosomal maturation in clearing receptors a...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Akbar, Mohammed Ali, Mandraju, Rajakumar, Tracy, Charles, Hu, Wei, Pasare, Chandrashekhar, Krämer, Helmut
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988897/
https://ncbi.nlm.nih.gov/pubmed/27496733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.07.010
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