The effect of statin treatment on intratumoral cholesterol levels and LDL receptor expression: a window-of-opportunity breast cancer trial

BACKGROUND: Deregulated lipid metabolism is common in cancer cells and the mevalonate pathway, which synthesizes cholesterol, is central in lipid metabolism. This study aimed to assess statin-induced changes of the intratumoral levels of cholesterol and the expression of the low-density lipoprotein...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Metab
Hauptverfasser: Feldt, Maria, Menard, Julien, Rosendahl, Ann H., Lettiero, Barbara, Bendahl, Pär-Ola, Belting, Mattias, Borgquist, Signe
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682108/
https://ncbi.nlm.nih.gov/pubmed/33292612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-020-00231-8
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