Statin-induced anti-proliferative effects via cyclin D1 and p27 in a window-of-opportunity breast cancer trial

PURPOSE: Cholesterol lowering statins have been demonstrated to exert anti-tumoral effects on breast cancer by decreasing proliferation as measured by Ki67. The biological mechanisms behind the anti-proliferative effects remain elusive. The aim of this study was to investigate potential statin-induc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Feldt, Maria, Bjarnadottir, Olöf, Kimbung, Siker, Jirström, Karin, Bendahl, Pär-Ola, Veerla, Srinivas, Grabau, Dorthe, Hedenfalk, Ingrid, Borgquist, Signe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424530/
https://ncbi.nlm.nih.gov/pubmed/25925673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0486-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados