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High expression of cholesterol biosynthesis genes is associated with resistance to statin treatment and inferior survival in breast cancer

There is sufficient evidence that statins have a protective role against breast cancer proliferation and recurrence, but treatment predictive biomarkers are lacking. Breast cancer cell lines displaying diverse sensitivity to atorvastatin were subjected to global transcriptional profiling and genes s...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kimbung, Siker, Lettiero, Barbara, Feldt, Maria, Bosch, Ana, Borgquist, Signe
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312337/
https://ncbi.nlm.nih.gov/pubmed/27458152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10746
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