WNT4 secreted by tumor tissues promotes tumor progression in colorectal cancer by activation of the Wnt/β-catenin signalling pathway

BACKGROUND: Wingless and Int-related protein (Wnt) ligands are aberrantly expressed in patients with colorectal cancer (CRC). However, the aberrant level of Wnt ligands in serum have not been explored. Here, we aimed to identify the levels of WNT4 in serum and explored its oncogenic role in CRC. MET...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Yang, Dongmei, Li, Qing, Shang, Renduo, Yao, Liwen, Wu, Lianlian, Zhang, Mengjiao, Zhang, Lihui, Xu, Ming, Lu, Zihua, Zhou, Jie, Huang, Li, Huang, Xiaodong, Cheng, Du, Yang, Yanning, Yu, Honggang
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682076/
https://ncbi.nlm.nih.gov/pubmed/33222684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01774-w
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