WNT4 secreted by tumor tissues promotes tumor progression in colorectal cancer by activation of the Wnt/β-catenin signalling pathway

BACKGROUND: Wingless and Int-related protein (Wnt) ligands are aberrantly expressed in patients with colorectal cancer (CRC). However, the aberrant level of Wnt ligands in serum have not been explored. Here, we aimed to identify the levels of WNT4 in serum and explored its oncogenic role in CRC. MET...

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Veröffentlicht in:J Exp Clin Cancer Res
Hauptverfasser: Yang, Dongmei, Li, Qing, Shang, Renduo, Yao, Liwen, Wu, Lianlian, Zhang, Mengjiao, Zhang, Lihui, Xu, Ming, Lu, Zihua, Zhou, Jie, Huang, Li, Huang, Xiaodong, Cheng, Du, Yang, Yanning, Yu, Honggang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682076/
https://ncbi.nlm.nih.gov/pubmed/33222684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01774-w
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