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E2A attenuates tumor-initiating capacity of colorectal cancer cells via the Wnt/beta-catenin pathway

BACKGROUND: The E2A gene, which encodes two basic helix–loop–helix transcription factors, E12 and E47, regulates colorectal cancer progression and epithelial-mesenchymal transition. However, whether E2A regulates the tumor-initiating capacity of colorectal cancer is unclear. Thus, we have studied E2...

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Detalles Bibliográficos
Publicado en:J Exp Clin Cancer Res
Main Authors: Zhao, Hongchao, Zhao, Chunlin, Li, Haohao, Zhang, Danhua, Liu, Guanghui
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591938/
https://ncbi.nlm.nih.gov/pubmed/31234887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1261-5
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