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The eIF4E homolog 4EHP (eIF4E2) regulates hippocampal long-term depression and impacts social behavior
BACKGROUND: The regulation of protein synthesis is a critical step in gene expression, and its dysfunction is implicated in autism spectrum disorder (ASD). The eIF4E homologous protein (4EHP, also termed eIF4E2) binds to the mRNA 5′ cap to repress translation. The stability of 4EHP is maintained thr...
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| Izdano u: | Mol Autism |
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| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7682028/ https://ncbi.nlm.nih.gov/pubmed/33225984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-020-00394-7 |
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