The eIF4E homolog 4EHP (eIF4E2) regulates hippocampal long-term depression and impacts social behavior

BACKGROUND: The regulation of protein synthesis is a critical step in gene expression, and its dysfunction is implicated in autism spectrum disorder (ASD). The eIF4E homologous protein (4EHP, also termed eIF4E2) binds to the mRNA 5′ cap to repress translation. The stability of 4EHP is maintained thr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Autism
Egile Nagusiak: Wiebe, Shane, Meng, Xiang Qi, Kim, Sung-Hoon, Zhang, Xu, Lacaille, Jean-Claude, Aguilar-Valles, Argel, Sonenberg, Nahum
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2020
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682028/
https://ncbi.nlm.nih.gov/pubmed/33225984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-020-00394-7
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