Ascorbic acid enhances low-density lipoprotein receptor expression by suppressing proprotein convertase subtilisin/kexin 9 expression

Ascorbic acid, a water-soluble antioxidant, regulates various biological processes and is thought to influence cholesterol. However, little is known about the mechanisms underpinning ascorbic acid-mediated cholesterol metabolism. Here, we determined if ascorbic acid can regulate expression of propro...

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Vydáno v:J Biol Chem
Hlavní autoři: Wang, Dandan, Yang, Xiaoxiao, Chen, Yuanli, Gong, Ke, Yu, Maoyun, Gao, Yongyao, Wu, Ximei, Hu, Huaqing, Liao, Chenzhong, Han, Jihong, Duan, Yajun
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
Lipids
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681026/
https://ncbi.nlm.nih.gov/pubmed/32913121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015623
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