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Pulse Dosing of Antibiotic Enhances Killing of a Staphylococcus aureus Biofilm

Biofilms are highly tolerant to antibiotics and underlie the recalcitrance of many chronic infections. We demonstrate that mature Staphylococcus aureus biofilms can be substantially sensitized to the treatment by pulse dosing of an antibiotic – in this case, oxacillin. Pulse (periodic) dosing was co...

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Pubblicato in:Front Microbiol
Autori principali: Meyer, Kirsten J., Taylor, Hannah B., Seidel, Jazlyn, Gates, Michael F., Lewis, Kim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680849/
https://ncbi.nlm.nih.gov/pubmed/33240251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.596227
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