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Pulse Dosing of Antibiotic Enhances Killing of a Staphylococcus aureus Biofilm

Biofilms are highly tolerant to antibiotics and underlie the recalcitrance of many chronic infections. We demonstrate that mature Staphylococcus aureus biofilms can be substantially sensitized to the treatment by pulse dosing of an antibiotic – in this case, oxacillin. Pulse (periodic) dosing was co...

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Detalhes bibliográficos
Main Authors: Kirsten J. Meyer, Hannah B. Taylor, Jazlyn Seidel, Michael F. Gates, Kim Lewis
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-11-01
Colecção:Frontiers in Microbiology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmicb.2020.596227/full
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