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Pulse Dosing of Antibiotic Enhances Killing of a Staphylococcus aureus Biofilm
Biofilms are highly tolerant to antibiotics and underlie the recalcitrance of many chronic infections. We demonstrate that mature Staphylococcus aureus biofilms can be substantially sensitized to the treatment by pulse dosing of an antibiotic – in this case, oxacillin. Pulse (periodic) dosing was co...
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| Publié dans: | Front Microbiol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7680849/ https://ncbi.nlm.nih.gov/pubmed/33240251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.596227 |
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