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Pulse Dosing of Antibiotic Enhances Killing of a Staphylococcus aureus Biofilm

Biofilms are highly tolerant to antibiotics and underlie the recalcitrance of many chronic infections. We demonstrate that mature Staphylococcus aureus biofilms can be substantially sensitized to the treatment by pulse dosing of an antibiotic – in this case, oxacillin. Pulse (periodic) dosing was co...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Meyer, Kirsten J., Taylor, Hannah B., Seidel, Jazlyn, Gates, Michael F., Lewis, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680849/
https://ncbi.nlm.nih.gov/pubmed/33240251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.596227
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