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Formulation of Aceclofenac Tablets Using Nanosuspension as Granulating Agent: An Attempt to Enhance Dissolution Rate and Oral Bioavailability

PURPOSE: The aim of the studies was to fabricate aceclofenac (AC) tablets using nanosuspension as granulating fluid to boost its rate of in vitro dissolution and eventually its oral bioavailability. METHODS: The optimized nanosuspension with particle size of 112±2.01 nm was fabricated using HPMC 1%...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Rahim, Haroon, Sadiq, Abdul, Ullah, Riaz, Bari, Ahmed, Amin, Fazli, Farooq, Umar, Ullah Jan, Naeem, Mahmood, Hafiz Majid
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680606/
https://ncbi.nlm.nih.gov/pubmed/33235448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S270746
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