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POISON EXON SPLICING REGULATES A COORDINATED NETWORK OF SR PROTEIN EXPRESSION DURING DIFFERENTIATION AND TUMORIGENESIS
The RNA isoform repertoire is regulated by splicing-factor (SF) expression, and alterations in SF-levels are associated with disease. SFs contain ultraconserved poison exon (PE) sequences, which exhibit greater identity across species than nearby coding exons, yet their physiological role and molecu...
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| Publicat a: | Mol Cell |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7680420/ https://ncbi.nlm.nih.gov/pubmed/33176162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.10.019 |
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