A computational and experimental approach toward a priori identification of alternatively spliced exons

Alternative splicing is a powerful means of regulating gene expression and enhancing protein diversity. In fact, the majority of metazoan genes encode pre-mRNAs that are alternatively spliced to produce anywhere from two to tens of thousands of mRNA isoforms. Thus, an important part of determining t...

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Bibliographic Details
Main Authors: PHILIPPS, DANA L., PARK, JUNG W., GRAVELEY, BRENTON R.
Format: Artigo
Language:Inglês
Published: Copyright 2004 by RNA Society 2004
Subjects:
Bioinformatics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370671/
https://ncbi.nlm.nih.gov/pubmed/15525709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7136104
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