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Chemoselective α-Sulfidation of Amides Using Sulfoxide Reagents

[Image: see text] The direct α-sulfidation of tertiary amides using sulfoxide reagents under electrophilic amide activation conditions is described. Employing convenient and readily available reagents, selective functionalization takes place to generate isolable sulfonium ions en route to α-sulfide...

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Bibliographic Details
Published in:Org Lett
Main Authors: Leypold, Mario, D’Angelo, Kyan A., Movassaghi, Mohammad
Format: Artigo
Language:Inglês
Published: American Chemical Society 2020
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680396/
https://ncbi.nlm.nih.gov/pubmed/33048547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c03160
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