Autoantibody-positive healthy individuals with lower lupus risk display a unique immune endotype

BACKGROUND: Autoimmune diseases comprise a spectrum of illnesses and are on the rise worldwide. Although anti-nuclear antibodies (ANA) are detected in many autoimmune diseases, up to 20% of healthy women are ANA+ and most will never develop clinical symptoms. Further, disease transition is higher am...

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Pubblicato in:J Allergy Clin Immunol
Autori principali: Slight-Webb, Samantha, Smith, Miles, Bylinska, Aleksandra, Macwana, Susan, Guthridge, Carla, Lu, Rufei, Merrill, Joan T., Chakravarty, Eliza, Arriens, Cristina, Munroe, Melissa E., Maecker, Holden T., Utz, Paul J., Guthridge, Joel M., James, Judith A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680268/
https://ncbi.nlm.nih.gov/pubmed/32446964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2020.04.047
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