Autoantibody‐Positive Healthy Individuals Display Unique Immune Profiles That May Regulate Autoimmunity

OBJECTIVE: Antinuclear antibodies (ANAs) are detected in ∼18% of females, yet autoimmune disease develops in only 5–8%. Immunologic differences between ANA‐positive healthy individuals and patients with systemic lupus erythematosus (SLE) may elucidate the regulatory mechanisms by which ANA‐positive...

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Udgivet i:Arthritis Rheumatol
Main Authors: Slight‐Webb, Samantha, Lu, Rufei, Ritterhouse, Lauren L., Munroe, Melissa E., Maecker, Holden T., Fathman, Charles G., Utz, Paul J., Merrill, Joan T., Guthridge, Joel M., James, Judith A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Systemic Lupus Erythematosus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042816/
https://ncbi.nlm.nih.gov/pubmed/27059145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39706
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