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Astrocytic pyruvate dehydrogenase kinase-2 is involved in hypothalamic inflammation in mouse models of diabetes

Hypothalamic inflammation plays an important role in disrupting feeding behavior and energy homeostasis as well as in the pathogenesis of obesity and diabetes. Here, we show that pyruvate dehydrogenase kinase (PDK)-2 plays a role in hypothalamic inflammation and its sequelae in mouse models of diabe...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Rahman, Md Habibur, Bhusal, Anup, Kim, Jae-Hong, Jha, Mithilesh Kumar, Song, Gyun Jee, Go, Younghoon, Jang, Il-Sung, Lee, In-Kyu, Suk, Kyoungho
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680139/
https://ncbi.nlm.nih.gov/pubmed/33219201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19576-1
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