Astrocytic pyruvate dehydrogenase kinase-2 is involved in hypothalamic inflammation in mouse models of diabetes

Hypothalamic inflammation plays an important role in disrupting feeding behavior and energy homeostasis as well as in the pathogenesis of obesity and diabetes. Here, we show that pyruvate dehydrogenase kinase (PDK)-2 plays a role in hypothalamic inflammation and its sequelae in mouse models of diabe...

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Publicado no:Nat Commun
Main Authors: Rahman, Md Habibur, Bhusal, Anup, Kim, Jae-Hong, Jha, Mithilesh Kumar, Song, Gyun Jee, Go, Younghoon, Jang, Il-Sung, Lee, In-Kyu, Suk, Kyoungho
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680139/
https://ncbi.nlm.nih.gov/pubmed/33219201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19576-1
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