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Pyruvate Dehydrogenase Kinase as a Potential Therapeutic Target for Malignant Gliomas

Metabolic aberrations in the form of altered flux through key metabolic pathways are the major hallmarks of several life-threatening malignancies including malignant gliomas. These adaptations play an important role in the enhancement of the survival and proliferation of gliomas at the expense of th...

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Autors principals: Jha, Mithilesh Kumar, Suk, Kyoungho
Format: Artigo
Idioma:Inglês
Publicat: The Korean Brain Tumor Society and The Korean Society for Neuro-Oncology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027103/
https://ncbi.nlm.nih.gov/pubmed/24904893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14791/btrt.2013.1.2.57
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