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Pyruvate Dehydrogenase Kinases: Therapeutic Targets for Diabetes and Cancers
Impaired glucose homeostasis is one of the risk factors for causing metabolic diseases including obesity, type 2 diabetes, and cancers. In glucose metabolism, pyruvate dehydrogenase complex (PDC) mediates a major regulatory step, an irreversible reaction of oxidative decarboxylation of pyruvate to a...
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| Udgivet i: | Diabetes Metab J |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Korean Diabetes Association
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4483603/ https://ncbi.nlm.nih.gov/pubmed/26124988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4093/dmj.2015.39.3.188 |
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