Computational design of mixed chirality peptide macrocycles with internal symmetry

Cyclic symmetry is frequent in protein and peptide homo‐oligomers, but extremely rare within a single chain, as it is not compatible with free N‐ and C‐termini. Here we describe the computational design of mixed‐chirality peptide macrocycles with rigid structures that feature internal cyclic symmetr...

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Detaylı Bibliyografya
Yayımlandı:Protein Sci
Asıl Yazarlar: Mulligan, Vikram Khipple, Kang, Christine S., Sawaya, Michael R., Rettie, Stephen, Li, Xinting, Antselovich, Inna, Craven, Timothy W., Watkins, Andrew M., Labonte, Jason W., DiMaio, Frank, Yeates, Todd O., Baker, David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley & Sons, Inc. 2020
Konular:
Full‐Length Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679966/
https://ncbi.nlm.nih.gov/pubmed/33058266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3974
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