Computational design of mixed chirality peptide macrocycles with internal symmetry

Cyclic symmetry is frequent in protein and peptide homo‐oligomers, but extremely rare within a single chain, as it is not compatible with free N‐ and C‐termini. Here we describe the computational design of mixed‐chirality peptide macrocycles with rigid structures that feature internal cyclic symmetr...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Protein Sci
Päätekijät: Mulligan, Vikram Khipple, Kang, Christine S., Sawaya, Michael R., Rettie, Stephen, Li, Xinting, Antselovich, Inna, Craven, Timothy W., Watkins, Andrew M., Labonte, Jason W., DiMaio, Frank, Yeates, Todd O., Baker, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley & Sons, Inc. 2020
Aiheet:
Full‐Length Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679966/
https://ncbi.nlm.nih.gov/pubmed/33058266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3974
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