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Involvement of FATP2-mediated tubular lipid metabolic reprogramming in renal fibrogenesis

Following a chronic insult, renal tubular epithelial cells (TECs) contribute to the development of kidney fibrosis through dysregulated lipid metabolism that lead to lipid accumulation and lipotoxicity. Intracellular lipid metabolism is tightly controlled by fatty acids (FAs) uptake, oxidation, lipo...

詳細記述

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書誌詳細
出版年:Cell Death Dis
主要な著者: Chen, Yuting, Yan, Qi, Lv, Mengyue, Song, Kaixin, Dai, Yue, Huang, Yi, Zhang, Le, Zhang, Cuntai, Gao, Hongyu
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679409/
https://ncbi.nlm.nih.gov/pubmed/33219209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03199-x
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