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Involvement of FATP2-mediated tubular lipid metabolic reprogramming in renal fibrogenesis
Following a chronic insult, renal tubular epithelial cells (TECs) contribute to the development of kidney fibrosis through dysregulated lipid metabolism that lead to lipid accumulation and lipotoxicity. Intracellular lipid metabolism is tightly controlled by fatty acids (FAs) uptake, oxidation, lipo...
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| Publié dans: | Cell Death Dis |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7679409/ https://ncbi.nlm.nih.gov/pubmed/33219209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03199-x |
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