Renal tubular epithelium-targeted peroxisome proliferator-activated receptor-γ maintains the epithelial phenotype and antagonizes renal fibrogenesis

Accumulating evidence suggests that loss of the renal tubular epithelial phenotype plays an important role in the pathogenesis of renal tubulointerstitial fibrosis. Systemic activation of peroxisome proliferator-activated receptor γ (PPAR-γ) has been shown to be protective against renal fibrosis, al...

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Pubblicato in:Oncotarget
Autori principali: Zhao, Min, Chen, Ying, Ding, Guixia, Xu, Ying, Bai, Mi, Zhang, Yue, Jia, Zhanjun, Huang, Songming, Zhang, Aihua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper: Pathology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323108/
https://ncbi.nlm.nih.gov/pubmed/27602490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11811
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