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PGC-1α overexpression protects against aldosterone-induced podocyte depletion: role of mitochondria

Growing evidence has shown that podocyte number is a critical determinant for the development of glomerulosclerosis and progressive renal failure. We previously reported that mitochondrial dysfunction (MtD) is an early event in podocyte injury. Peroxisome proliferator-activated receptor-γ coactivato...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Zhao, Min, Yuan, Yanggang, Bai, Mi, Ding, Guixia, Jia, Zhanjun, Huang, Songming, Zhang, Aihua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914275/
https://ncbi.nlm.nih.gov/pubmed/26943584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7859
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