Single-cell analysis of autophagy activity in normal and de novo transformed human mammary cells

Assessment of autophagy activity has historically been limited to investigations of fixed tissue or bulk cell populations. To address questions of heterogeneity and relate measurements to functional properties of viable cells isolated from primary tissue, we created a lentiviral (RFP-GFP-MAP1LC3B) v...

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Publicat a:Sci Rep
Autors principals: Lefort, Sylvain, Balani, Sneha, Pellacani, Davide, Guyot, Boris, Gorski, Sharon M., Maguer-Satta, Véronique, Eaves, Connie J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679376/
https://ncbi.nlm.nih.gov/pubmed/33219251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77347-w
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