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Circumventing the Crabtree effect: forcing oxidative phosphorylation (OXPHOS) via galactose medium increases sensitivity of HepG2 cells to the purine derivative kinetin riboside

Small-molecule compound-based therapies have provided new insights into cancer treatment against mitochondrial impairment. N6-furfuryladenosine (kinetin riboside, KR) is a purine derivative and an anticancer agent that selectively affects the molecular pathways crucial for cell growth and apoptosis...

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Detalhes bibliográficos
Publicado no:Apoptosis
Main Authors: Orlicka-Płocka, Marta, Gurda-Wozna, Dorota, Fedoruk-Wyszomirska, Agnieszka, Wyszko, Eliza
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679298/
https://ncbi.nlm.nih.gov/pubmed/32955614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-020-01637-x
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