Design, Synthesis, and Evaluation of Novel 3-Carboranyl-1,8-Naphthalimide Derivatives as Potential Anticancer Agents

We synthesized a series of novel 3-carboranyl-1,8-naphthalimide derivatives, mitonafide and pinafide analogs, using click chemistry, reductive amination and amidation reactions and investigated their in vitro effects on cytotoxicity, cell death, cell cycle, and the production of reactive oxygen spec...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Rykowski, Sebastian, Gurda-Woźna, Dorota, Orlicka-Płocka, Marta, Fedoruk-Wyszomirska, Agnieszka, Giel-Pietraszuk, Małgorzata, Wyszko, Eliza, Kowalczyk, Aleksandra, Stączek, Paweł, Bak, Andrzej, Kiliszek, Agnieszka, Rypniewski, Wojciech, Olejniczak, Agnieszka B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7967199/
https://ncbi.nlm.nih.gov/pubmed/33803403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052772
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