Design, Synthesis, and Evaluation of Novel 3-Carboranyl-1,8-Naphthalimide Derivatives as Potential Anticancer Agents

We synthesized a series of novel 3-carboranyl-1,8-naphthalimide derivatives, mitonafide and pinafide analogs, using click chemistry, reductive amination and amidation reactions and investigated their in vitro effects on cytotoxicity, cell death, cell cycle, and the production of reactive oxygen spec...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Rykowski, Sebastian, Gurda-Woźna, Dorota, Orlicka-Płocka, Marta, Fedoruk-Wyszomirska, Agnieszka, Giel-Pietraszuk, Małgorzata, Wyszko, Eliza, Kowalczyk, Aleksandra, Stączek, Paweł, Bak, Andrzej, Kiliszek, Agnieszka, Rypniewski, Wojciech, Olejniczak, Agnieszka B.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7967199/
https://ncbi.nlm.nih.gov/pubmed/33803403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052772
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